Most cases of bowel cancer first develop inside clumps of cells on the inner lining of the bowel. These clumps are known as polyps. However, if you develop polyps, it does not necessarily mean you will get bowel cancer.
Exactly what causes cancer to develop inside the bowel is still unknown. However, research has shown several factors may make you more likely to develop it. These factors are outlined below.
Your chances of developing bowel cancer increase as you get older. Almost 9 out of 10 cases of bowel cancer in the UK are diagnosed in people over the age of 60.
Having a family history of bowel cancer can increase your risk of developing the condition yourself, particularly if a close relative (mother, father, brother or sister) was diagnosed with bowel cancer below the age of 50.
If you are particularly concerned that your family’s medical history may mean you are at an increased risk of developing bowel cancer, it may help to speak to your doctor.
If necessary, your doctor can refer you to a genetics specialist, who can offer more advice about your level of risk and recommend any necessary tests to periodically check for the condition.
A large body of evidence suggests a diet high in red and processed meat can increase your risk of developing bowel cancer.
For this reason, the Department of Health advises people who eat more than 90g (cooked weight) a day of red and processed meat cut down to 70g a day.
There is also evidence that suggests a diet high in fibre could help reduce your bowel cancer risk.
People who smoke cigarettes are more likely to develop bowel cancer, other types of cancer, and other serious conditions, such as heart disease.
Drinking alcohol has been shown to be associated with an increased risk of bowel cancer, particularly if you regularly drink large amounts.
Being overweight or obese is linked to an increased risk of bowel cancer, particularly in men.
If you are overweight or obese, losing weight may help lower your chances of developing the condition.
People who are physically inactive have a higher risk of developing bowel cancer.
You can help reduce your risk of bowel and other cancers by being physically active every day.
Some conditions affecting the bowel may put you at a higher risk of developing bowel cancer. For example, bowel cancer is more common in people who have had severe Crohn’s disease or ulcerative colitis for many years.
If you have one of these conditions, you will usually have regular check-ups to look for signs of bowel cancer from about 10 years after your symptoms first develop.
Check-ups will involve examining your bowel with a colonoscope – a long, narrow flexible tube that contains a small camera – that is inserted into your rectum.
The frequency of the colonoscopy examinations will increase the longer you live with the condition, and will also depend on factors such as how severe your ulcerative colitis is and if you have a family history of bowel cancer.
There are two rare inherited conditions that can lead to bowel cancer. They are:
Although the polyps caused by FAP are non-cancerous, there is a high risk that, over time, at least one will turn cancerous. Most people with FAP will have bowel cancer by the time they are 50.
As people with FAP have such a high risk of getting bowel cancer, they are often advised by their doctor to have their large bowel removed before they reach the age of 25.
Removing the bowel as a precautionary measure is also usually recommended in people with HNPCC because the risk of developing bowel cancer is so high.
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Source: NHS UK